Why Are the Most Commonly Prescribed Infertility Treatment Medicines Not Always Effective?

Reviewed by Dr. Sourabh Welling, Founder

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Many couples are started on fertility medicines such as clomiphene citrate or on intrauterine insemination (IUI) after only basic tests. These treatments do help certain people, but research shows they are not equally effective for everyone, and understanding why can save time, money and emotional strain.

When they work well

Clomiphene (sold as Clomid or Serophene) stimulates ovulation. It is effective in women who do not ovulate regularly, for example because of PCOS.

When the benefit is limited

Large trials in couples with unexplained infertility, where ovulation is already normal, found that clomiphene and IUI added little over a period of simply trying naturally with good timing. In such couples, the medicine is addressing a problem that may not be present.

Possible downsides

  • Multiple pregnancy, which carries higher risks for mother and babies
  • Side effects such as hot flushes, mood changes, headaches and a thinner womb lining
  • With stronger injectable drugs, ovarian hyperstimulation syndrome
  • Months spent on a treatment that does not address the actual cause

The importance of finding the cause

Before starting treatment, it helps to confirm ovulation, check the tubes and womb, test the thyroid and prolactin, and carry out a semen analysis for the male partner. Homeopathic treatment aims to look at the individual as a whole and can be considered alongside this evaluation. Please do not stop or change prescribed medicines without discussing it with your fertility doctor.

Learn more

To discuss your situation with a Welling Homeopathy doctor, contact a clinic or call +91 80 80 850 950 for a consultation in person or online.

Disclaimer: this page is for information only and is not a substitute for professional medical advice, diagnosis or treatment. Results vary from person to person.

Dr. Sourabh Welling, founder of Welling Homeopathy

Reviewed by

Dr. Sourabh Welling — Founder

Dr. Sourabh Welling is a practicing homeopathy doctor and founder of Welling Homeopathy, Mumbai, with 24 years of clinical experience. A multiple award winner at national and international levels, he focuses on individualized homeopathic care for chronic and complex health conditions. He leads a team of experienced doctors providing personalized consultations based on each patient’s symptoms, health history and individual circumstances.

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